Skin Science

What are peptides and what are the benefits for your skin?

by Neostrata
May 15, 2024

If you're not using peptides in your skin care regimen, you're missing out on a powerhouse ingredient with the potential to visibly improve a multitude of skin concerns. Read on to learn all about topical cosmetic peptides and how you can add this small, but mighty ingredient into your daily routine.

What are peptides and what do they do for your skin?

Peptides are a key building block of proteins and are made up of short chains of anywhere between 2 and 50 amino acids1. Larger chains of amino acids make up proteins. While our bodies produce peptides, adding topical skin care products with peptides can help support structural proteins like collagen and elastin for skin that's visibly healthier and younger looking. With the multi-action benefits peptides offer, it's no wonder why they've become a mainstay ingredient in supplements and skin care products.

What are the benefits of peptides?

Did you know that there are different peptides that can address different skin concerns? There are peptides to help support collagen and elastin for smoother, firmer looking skin, peptides to help brighten and even skin tone and provide antioxidant benefits. There are even peptides designed to soothe sensitive skin and provide plumping hydration.

Peptides are also popular in skin care formulations because they're known to be more gentle than other topical antiaging ingredients like Retinol and Glycolic Acid, making peptides an ideal ingredient for all skin types, even sensitive and reactive skin.

As the science behind topical peptides continues to advance, new and intriguing forms of this ingredient are being incorporated into products and daily regimens. One such technology is MicroDiPeptide229®, a patented breakthrough technology that visibly lifts, firms, and sculpts the skin.

What is a MicroDiPeptide?

A Dipeptide is made up of two amino acids linked by a single bond. Dipeptides are small by nature and this small size helps aid molecule absorption into skin's surface layers. Users benefit from these small molecules because they start working in the skin quickly and efficiently.

Why do the size of molecules matter in your skincare routine?

When it comes to skin care ingredients, molecule size is an important consideration. Let's look at the science behind molecule size.

A Dalton is the standard measure of molecule size. When it comes to the ability of skin care ingredients to penetrate the skin's surface, scientific research shows that 500 Daltons is the threshold where molecules can easily pass through the skin barrier. Molecules larger than 500 Daltons sit on the skin's surface and take longer to absorb, contrasted with ingredients smaller than 500 Daltons which easily penetrate the skin's surface layers and absorb more efficiently.

NEOSTRATA MicroDiPeptide229® technology weighs in at 229 Daltons and provides enhanced absorption, plus noticeable antiaging benefits.

What makes MicroDiPeptide229® different?

MicroDiPeptide229® is a unique, patented peptide technology, backed by over eight years of clinical research and development at NEOSTRATA, MicroDiPeptide229® is 2.5 times smaller than leading topical cosmetic peptides, enhancing absorption into skin's surface layers.

This dipeptide technology is an antiaging powerhouse that targets 5 markers of skin's matrix, including pro-collagen, elastin and hyaluronic acid for skin that's visibly smoother, firmer and more even toned. This peptide also targets a more sculpted jawline and facial contour for a more youthful complexion.

MicroDiPeptide229® is a gentle ingredient with antiaging and soothing benefits for those with sensitive or reactive skin, meaning anyone can benefit from this patented technology. These benefits have been backed up by multiple clinical studies.

What are the benefits of MicroDiPeptide229®?

Skin care peptides support collagen and elastin stimulation, boost hydration, enhance antioxidant protection. They can promote brighter, more even toned skin and visible reduction of fine lines and wrinkles.

The benefits of using peptides are enhanced when opting for those with a molecular weight under 500 Daltons. At 229 Daltons, MicroDiPeptide229® offers superior absorption that targets 5 key markers of skin's supportive matrix for visibly firmer, brighter and smoother skin with a more sculpted, contoured and defined look.

How to use MicroDiPeptide229® in your skincare

We've supercharged our Skin Active collection with MicroDiPeptide229® and now you can reap the benefits of our patented antiaging technology as part of our the NEOSTRATA Peptide Power Regimen.

How to use the NEOSTRATA Peptide Power Regimen:

FIRST: Start with your cleanser of choice. We love Skin Active Exfoliating Wash, a foaming PHA face wash that gently exfoliates to prepare skin for the regimen to follow.

FOLLOW: Follow with your neck treatment.

  • Triple Firming Neck Cream: This cult favorite is your next-level neck cream. MicroDiPeptide229® is combined with complementary skin smoothing and exfoliating ingredients in a non-greasy formula created especially for the needs of the delicate neck area while promoting a smoother and firmer look.

FINISH: Finish with a treatment moisturizer.

  • Rebound Sculpting Cream: Finish your daily regimen with this silky, light textured moisturizer formulated with MicroDiPeptide229®, an AHA/PHA blend and other benefit ingredients for radiant, hydrated more youthful looking skin. 70% of our study participants said their skin looked up to 5 years younger after 16 weeks of twice daily use!

Peptides are a powerful ingredient to add pep to your skin. They take on a wide range of concerns and work well on all skin tones and skin types – they're even gentle enough for sensitive skin.

When selecting skin care ingredients, size matters! Ingredients with a molecule size under 500 Daltons, like NEOSTRATA patented MicroDiPeptide229® technology allow for better absorption of ingredients, allowing your products to work efficiently and effectively by quickly penetrating the skin's surface layers.

NEOSTRATA patented MicroDiPeptide229® technology is a breakthrough technology backed by over 8 years of research and development and has been featured in multiple clinical posters and talks at worldwide medical conferences.

Peptides can play a role in many steps of your daily skin care regimen, including serums, eye cream, neck cream and moisturizers. Consistent use of these ingredients can target signs of skin aging, uneven skin tone, dryness and sensitivity with visible results that continue to improve over time.

If you're not sure where to start, begin with a peptide serum or treatment product Triple Firming Neck Cream or Rebound Sculpting Cream.



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